Nicotinic modulation of glutamatergic synaptic transmission in region CA3 of the hippocampus
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چکیده
منابع مشابه
Nicotinic modulation of glutamatergic synaptic transmission in region CA3 of the hippocampus.
Cholinergic modulation of synaptic transmission in the hippocampus appears to be involved in learning, memory and attentional processes. In brain slice preparations of hippocampal region CA3, we have explored the effect of nicotine on the afferent connections of stratum lacunosum moleculare (SLM) vs. the intrinsic connections of stratum radiatum (SR). Nicotine application had a lamina-selective...
متن کاملModulation of Basal Glutamatergic Transmission by Nicotinic Acetylcholine Receptors in Rat Hippocampal Slices
Objective(s) Nicotinic acetylcholine receptors (nAChRs) regulate epileptiform activity and produce a sustained pro-epileptogenic action within the hippocampal slices. In the present study, we investigated the effect of nAChRs on evoked glutamatergic synaptic transmission in area CA3 and CA1 of rat hippocampal slices to identify possible excitatory circuits through which activation of nAChRs pr...
متن کاملIdentification of the kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus.
To understand the physiological role of kainate receptors and their participation in seizure induction in animal models of epilepsy, it will be necessary to develop a comprehensive description of their action in the CA3 region of the hippocampus. Activation of presynaptic kainate receptors depresses excitatory synaptic transmission at mossy fiber and associational-commissural inputs to CA3 pyra...
متن کاملCholinergic modulation of excitatory synaptic transmission in the CA3 area of the hippocampus.
Cholinergic innervation of the hippocampus has been implicated in memory formation and retrieval. Here we study cholinergic modulation of excitatory transmission in the CA3 area of the rat hippocampus. We used a combination of optical measurements of presynaptic calcium and electrophysiological measurements of synaptic currents to study associational-commissural (A/C) and mossy fiber (MF) synap...
متن کاملmodulation of basal glutamatergic transmission by nicotinic acetylcholine receptors in rat hippocampal slices
objective(s) nicotinic acetylcholine receptors (nachrs) regulate epileptiform activity and produce a sustained pro-epileptogenic action within the hippocampal slices. in the present study, we investigated the effect of nachrs on evoked glutamatergic synaptic transmission in area ca3 and ca1 of rat hippocampal slices to identify possible excitatory circuits through which activation of nachrs pro...
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ژورنال
عنوان ژورنال: European Journal of Neuroscience
سال: 2005
ISSN: 0953-816X,1460-9568
DOI: 10.1111/j.1460-9568.2005.04494.x